Recent Research

Stay up-to-date on the advancing field of HCT with short summaries and links to the most relevant published research.

Gooptu M, et al., Blood—An observational study from the CIBMTR Graft Sources Working Committee found that 8/8 matched unrelated donor hematopoietic cell transplantation (HCT) with PTCy based graft versus host disease (GVHD) prophylaxis resulted in superior overall survival and disease-free survival compared to haploidentical HCT with PTCy in the reduced intensity conditioning (RIC) setting for treatment of acute leukemia and myelodysplastic syndromes. It is the first known study that offers a direct comparison between the two donor sources using PTCy.

Use of MMUDs can expand HCT access for ethnically diverse populations.

Auletta J, et al., Transplantation and Cellular Therapy—A manuscript published in Transplantation and Cellular Therapy offered the first report on the impact of the COVID-19 pandemic on the ability of the National Marrow Donor Program® (NMDP)/Be The Match® and the Network to safely deliver unrelated donor products early in the pandemic. The authors found that the NMDP/Be The Match and Network partners continued to effectively deliver domestic and unrelated donor products to allogeneic transplant patients in similar or shorter timeframes than before COVID-19, despite the many unexpected challenges brought about by the pandemic.

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