Recent Research

Liberio N, et al. – The CIBMTR conducted a study to address the lack of data guiding haploidentical (haplo) donor selection for pediatric HCT. Research presented at the European Society for Blood and Marrow Transplantation (EBMT) Annual Meeting showed that sibling donors had a lower risk of acute and chronic graft-versus-host disease and graft failure when compared to parental donors. The study suggests sibling donors may be the optimal haplo donor choice for pediatric HCT to minimize risks and improve outcomes.

Mehta R, et al.  – Research published in Transplantation and Cellular Therapy shows better outcomes for matched unrelated donor and matched sibling donor hematopoietic cell transplantation (HCT) than haploidentical donor HCT when using post-transplant cyclophosphamide for graft-versus-host disease prevention in a single center study.

Murthy GSG, et al.  – Research published in JAMA Oncology finds relapse and disease-free survival advantages when using younger matched unrelated donors over older matched sibling donors for patients undergoing allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome.

Khera N, et al. – Research presented at the 63rd American Society of Hematology (ASH) Annual Meeting and Exposition shows that rates of autologous and allogeneic hematopoietic cell transplants (HCT) have increased more rapidly among African American, Hispanic, and other underserved populations than among non-Hispanic whites from 2009 to 2018. However, a challenge still exists to close the gaps in overall survival for African American and other pediatric patients.