Amy Strelzer Manasevit Research Program
The Amy Strelzer Manasevit Research Program for the Study of Post-Transplant Complications (Amy Research Program) is one of the largest and most coveted grants in the field of transplantation and cellular therapy. The grant supports the research endeavors of scientists and clinicians early in their careers. Its goal is to launch these young investigators on a life-long journey to discover solutions to potentially life-threatening post-transplant or post-cellular therapy complications such as infection, relapse or graft-versus-host disease.
The emphasis on early support attracts new talent to the field and encourages the researchers to focus on these complications throughout their careers. Amy Scholars receive a maximum of $400,000 divided over five years from the Be The Match Foundation®. This crucial funding enables the researchers to continue with their projects consistently without having to stop and apply for further financial support.
2019 Requirements and Conditions of the Amy Strelzer Manasevit Research Program
- The research proposal must address complications arising after
allogeneic hematopoietic cell transplantation (HCT) or a cellular therapy
directed at a disease traditionally treated by HCT. The cellular therapy being
studied does not have to be given in conjunction with an HCT. Post-transplant
or post-cellular therapy complications are defined as acute and late
complications, including relapse.
- Proposals may describe either clinical or pre-clinical investigations.
Clinical investigations include observational human research, prospective
interventional clinical trials in humans, and ancillary laboratory studies
performed in conjunction with a human prospective clinical trial. Pre-clinical
investigations include laboratory-based human and/or animal studies designed to
test the mechanisms, safety, and efficacy of an intervention prior to or in
conjunction with its application in humans. Proposals must have only one
principal investigator, the applicant, and no co-investigators.
- Up to three awards will be made, and depending on the number and quality
of proposals received, at least one clinical proposal and one pre-clinical
proposal will be awarded, for a maximum of $400,000 in support over five years.
Payments will be made in segments; upon receipt of grant, at 12-month reporting
milestones and upon receipt of final report.
- Applicants must:
- Have received a doctoral degree (M.D., Ph.D., D.O. or equivalent) within the past ten years (January 1, 2009 or later) in a field pertinent to the award. If the applicant has more than one relevant doctoral degree, the date the most recent relevant doctoral degree was obtained will be used to determine eligibility. Upon evaluation, the “within ten years of most recent degree” requirement may be increased to more than ten years if the applicant can document that his/her career was interrupted due to extended medical or family leave.
- Not hold an RO1 or equivalent research grant at the time of the award.
- Hold a position in a U.S. facility at the time of the application and award. Awardees may transfer the award to another facility during the award period if a written request with justification is submitted to the NMDP for review and approval.
- Be a U.S. citizen, permanent resident or foreign citizen holding a valid U.S. visa.
- If credentials for eligibility are uncertain or require evaluation, please email Roberta King at firstname.lastname@example.org.
- Proposals must be submitted by Friday, November 2, 2018.
- The Awards Committee will select up to three scholars for the funding
period July 1, 2019 through June 30, 2024. Awardees will be announced at the 2019
Transplantation and Cellular Therapy Meetings in Houston, Texas, February 20-24,
The program was established in 1997 to honor the memory of Amy Strelzer
Manasevit. A vibrant young mother of two, Amy was diagnosed with multiple
myeloma in 1993. After receiving a successful marrow transplant, she succumbed
to pneumonia and passed away six weeks after returning home. Manasevit’s family
and friends partnered with NMDP/Be The Match to establish the research program
in the hope they could prevent other families from losing their loved ones.
To date, Be The Match Foundation has supported 37 scholars and 13
post-doctoral fellows. The Amy Scholars were collectively awarded just under $9
million and have leveraged their Amy research to secure an additional $110 million
in research funding.
Contact us for more information about the Amy Strelzer Manasevit Research Program.