Updates for Donor, Apheresis/Collection and Recruitment Centers
Up-to-date information on NMDP/Be The Match response to COVID-19
Updated April 7, 2020
Our Business Continuity, Donor Operations and Patient Operations teams continue their daily review of the information coming from the CDC and agencies like the World Marrow Donor Association (WMDA).
As new information becomes available, we will update this page with information to guide you. As always, the health and safety for our donors and patients is our highest priority.
Click on the topics below to jump to that section:
- Essential Collections at Apheresis and Collection Centers (updated 3/24/20)
- Letter for Donors Under Shelter-In-Place Orders (updated 4/6/2020)
- Support for Overcoming Donor or Courier Travel Restrictions (updated 4/2/2020)
- Preparing Donors for Travel (updated 4/7/2020)
- Change to Confirmatory Typing Process (updated 3/24/20)
- Donor center process for bone marrow requests during COVID-19 pandemic (updated 3/27/2020)
- Re-evaluation of Donor Travel (updated 3/19/2020)
- COVID-19 Impacts on Vendor Partners (updated 3/19/2020)
- Novel Coronavirus (COVID-19) Infection Assessment Questionnaire (updated 3/16/2020)
- FDA Guidance on Donor Screening for COVID-19 (updated 4/3/2020)
- Assessment of Donor Foreign Travel (updated 4/1/2020)
- Assessment of Donor Travel in the U.S. (updated 4/1/2020)
- Standardized Actions for Donors who are Health Care Workers Working with COVID-19 Patients (updated 4/1/2020)
- Notification of Donor COVID-19 Diagnosis Post-Donation (updated 4/1/2020)
- Membership, Engagement, Enrollment and Experience Live Drives Paused (updated 3/26/2020)
- Cancellation of Be The Match Mexico Recruitment Events (updated 3/19/2020)
- Frequently Asked Questions for Donor Centers and Your Donors (updated 3/20/2020)
- Frequently Asked Questions for Apheresis Centers and Collection Centers (updated 3/27/2020)
- Donor Services Webinar (updated 3/24/19)
Donor Assessment and Collection
Letters for Donors and Companions Under Shelter-In-Place Orders (updated 4/6/2020)
Many states are enacting shelter-in-place orders to help contain the spread of COVID-19. To ensure donors do not have issues getting to and from appointments, we have developed a letter for donors and their companions to carry with them when they need to leave home for donation-related appointments (e.g., workup or collection).
If local authorities stop a donor, the donor should show the officer the letter.
Download the Donor Travel Letter and Donor Companion Travel Letter from the “Resources and Information for Donors” webpage. Then, fill in the appropriate information and send it to the donor.
State-specific letters for donors and companions during the COVID-19 pandemic
Some states have different requirements for their documentation. Please use the state-specific documents on the “Resources and Information Donors” webpage in place of the general documents for donors and companions traveling in these states:
Support for Overcoming Donor or Courier Travel Restrictions (updated 4/2/2020)
As states and cities continue to tighten travel restrictions, freedom of movement may become restricted for our donors and couriers. The NMDP/Be The Match Emergency Preparedness Team (EPT) is available to intervene.
The team’s goal is to assist donors and couriers who are faced with restrictions that make travel for our life-saving mission seem impossible. If you have a specific donor or courier who is facing a COVID-19-related travel impact within up to 48 hours (including those facing immediate impacts), use our “Request for Assistance for Donor/Courier” template. The template is also available on our Resources and Information for Donors webpage.
Copy and paste the information from the template into an email, fill out the necessary information and send the email to DonorServicesLiaisons@nmdp.org.
Our Partner Liaisons will coordinate assistance with the EPT upon receiving your email.
Preparing Donors for Travel (updated 4/7/2020)
Donor travel for pre-donation appointments and collection could be impacted, whether your donors are traveling by car or plane. Use the following recommendations to help your donors prepare for all situations and stay on track for donation.
Check with your donors and their companions to see if their location requires documentation for being out of the house during local or statewide shelter-in-place orders. Provide them with the general letter or state-specific letter to carry with them. Download the appropriate Donor Travel Letter and Donor Companion Travel Letter.
Cloth face coverings
Per the CDC guidelines, we recommend donors and their companions use a cloth face covering in public settings when social distancing is difficult. Connect with your donors and their companions to make sure they have access to cloth face coverings. If they do not, please provide masks for them and/or provide them with instructions on how to make them at home. The CDC website provides sew and no-sew tutorials.
Arrival instructions and companion restrictions
Apheresis and collection centers are evolving their response to COVID-19. The center may have changed arrival instructions. Some may no longer allow companions to accompany donors. Check with the apheresis or collection centers before your donors’ visits and provide your donors with the most up-to-date information about screening, what to expect and any additional instructions about the center's COVID-19 protocols.
Some states have set up checkpoints that may impact travel times. If your donors are driving to any of their appointments and crossing state lines, encourage them to educate themselves about any potential traffic disruptions while planning their trip.
Novel Coronavirus (COVID-19) Infection Assessment Questionnaire (updated 3/16/2020)
The NMDP/Be The Match has amended the F01190 Novel Coronavirus (COVID-19) Infection Assessment Questionnaire. The amendment is in response to the evolving COVID-19 outbreak and an ongoing focus on identifying donors with the highest risk of exposure.
Transplant centers will receive information on the donor’s travel history and potential exposures. This will allow them to make more informed risk/benefit decisions.
At this time, the NMDP/Be The Match will not defer donors for any travel risk. It is the transplant center’s decision on whether to proceed with a donor.
Access the summary of changes to Form F01190.
FDA Guidance on Donor Screening for COVID-19 (updated 4/3/2020)
On April 1, 2020, the FDA released updated information on COVID-19 for organizations collecting human cell and tissue products (HCT/Ps), including marrow and PBSC. Like other respiratory viruses, there is currently no evidence that COVID-19 is transmitted via blood or stem cell products.
Therefore, the FDA does not recommend laboratory testing to screen asymptomatic donors for COVID-19. Instead, the FDA continues to recommend organizations evaluate potential donors based on known risks.
As a reminder, the following procedures are in place for screening donors before and after donation.
We are gathering additional health and travel information from donors at the confirmatory typing, held for workup and workup stages using the amended Health History Screening Questionnaire.
Following donation, donors will be contacted at regular intervals: 2 days post; 1 week post; 1 month post; and in between as needed. Additionally, all donors are being counseled to contact their individual workup specialists if:
- They are diagnosed with COVID-19
- Learn of exposure to a person diagnosed with COVID-19
- Develop any acute infectious symptoms prior to and following donation
Pre-donation screening and pertinent post-donation findings will be reported to the transplant center. If a donor from DC001 reports a positive COVID-19 diagnosis within 30 days after donation, the NMDP/Be The Match will also notify the apheresis or collection center.
Assessment of Donor Foreign Travel (updated 4/1/2020)
While the CDC Travel Recommendations by Country recently changed to a Level 3 Health Notice or Travel Health Notice for all countries, there are no planned changes to the F01190, Novel Coronavirus (COVID-19) Infection Assessment Questionnaire.
It remains important to collect information on donor travel outside the U.S. and report this information to the transplant center.
With all countries at a Level 3, this means the Case Manager and transplant center must be notified about any donor who has traveled anywhere outside the U.S. in the past 30 days or plans to travel outside the U.S. in the upcoming two months.
As the outbreak is contained, countries will begin to move to Level 1 and 2 Notices. The F01190, Novel Coronavirus (COVID-19) Infection Assessment Questionnaire contains a link to the CDC Travel Recommendation by Country webpage.
Assessment of Donor Travel in the U.S. (updated 4/1/2020)
With the extensive spread of the COVID-19 infection in the U.S., there are currently no plans to gather or report donor travel to specific locations in the U.S. Because the virus is in all 50 states, it is reasonable to assume most people have had some type of exposure to COVID-19. While there are “hot spots” in the U.S., these locations change rapidly.
We will continue to use the F01190, Novel Coronavirus (COVID-19) Infection Assessment Questionnaire at the confirmatory typing, held for workup and workup stages. Transplant centers will be notified if a donor reports close contact to a person with presumed or suspected COVID-19 infection but is not reporting symptoms themselves.
Standardized Actions for Donors who are Health Care Workers Working with COVID-19 Patients (updated 4/1/2020)
Health care workers (HCW) who are requested as donors may have different levels of exposure to COVID-19. We have established standardized actions based on different situations for HCWs that depend on their exposures:
Situation 1: HCW with prolonged exposure providing direct care and/or exposure to bodily fluids of one or more confirmed or presumptive COVID-19 cases
Take this action:
- Status as Temporarily Unavailable for 3 months from HHSQ
- Share with Case Manager/transplant center: “TU is estimate; HCW ongoing COVID-19 exposure”
This group includes HCWs or other professionals in acute and long-term care facilities and staff working with ventilators, intubated patients, patients with tracheostomies or anything else that aerosolizes respiratory droplets.
Situation 2: HCW working in medical setting with patients but none with known COVID-19 infection
Take this action:
- Evaluate as any other potential donor assessing for known exposures or their own symptoms
Situation 3: Person living with HCW
Take this action:
- Evaluate as any other potential donor assessing for known exposures or their own symptoms
Situation 4: HCW under Mandatory Medical Quarantine*
Take this action:
- Status as Temporarily Unavailable until quarantine timeline expires
- If their test results are pending, wait until results are known
*Any potential donor under mandatory medical quarantine would be assessed as described.
If it is known that a current donor at workup is an HCW and is in the high-risk category, then the donor should be made Temporarily Unavailable for 3 months. All current and new donors need to be assessed to determine if they fall into category 1. This assessment and these guidelines are due to the understanding that these workers are at higher risk of exposure and that they might be at higher risk for quarantine or illness and then unavailable for donation.
Notification of Donor COVID-19 Diagnosis Post-Donation (updated 4/1/2020)
If a donor from DC001 reports a positive COVID-19 diagnosis within 30 days after donation, the NMDP/Be The Match will notify the apheresis or collection center.
We will provide the:
- Date of positive test
- Onset of donor symptoms
- Any known exposures if applicable
We are providing this information so apheresis and collection centers can inform health care team members who may have come in close contact with a potentially infectious donor on collection day.
The donor’s Workup Specialist and NMDP/Be The Match Medical Services will notify the apheresis or collection center via email. Donor centers should download and send the Post Donation COVID-19 Positive Notification form to the apheresis or collection centers. Apheresis and collection center staff can download a sample form to familiarize yourself with the information you will receive.
The transplant center will also receive similar information about a donor who receives a COVID-19 diagnosis.
If you have any questions, please email DMS@nmdp.org.
Change to Confirmatory Typing Process (updated 3/24/2020)
As a result of the limited travel conditions brought on by the COVID-19 pandemic, the confirmatory typing (CT) process has changed to reduce the number of times a potential donor must visit a draw site prior to collection. Effective March 25, 2020, donor centers will request a donor at CT as normal, however, most CTs will not include blood draws for HLA testing or IDM results.
Instead, the donor center will check for donor availability, complete the HHSQ with the donor, and communicate updates to the Case Manager. Available donors may be requested for HR, Held for Workup, or Workup (with no additional HHSQ needed if the next request is made within 12 weeks). A buccal swab will be completed at HR if necessary.
With this change, Case Managers, Search Advocates and donor center staff will remain in close contact to maintain a line of sight to the transplant center’s needs.
We have put a variance in place to account for these changes. Reference variance number VAR-00062 in the donor’s file. Contact your liaison (DonorServicesLiaison@NMDP.ORG) with questions.
Donor center process for bone marrow requests during COVID-19 pandemic (updated 3/27/2020)
During the COVID-19 pandemic, we are asking transplant centers to reserve marrow requests for patients with the greatest need for this graft source. Effective March 27, 2020, this means donor centers should assume new requests that are marrow only truly need marrow based on the patient status and should proceed accordingly.
For new workup requests that come through indicating marrow as the first choice and PBSC as the second choice, first assess whether a marrow collection facility is in close proximity to the donor. This would allow the donor to avoid or limit their travel.
If you can locate a local facility, try proceeding with securing a marrow collection that meets the transplant center’s requested timeline.
If you cannot find a local facility, alert the Case Manager that you will now be proceeding with locating and securing a PBSC collection that meets the transplant center’s requested timeline.
Please note, if the product is marrow and not being cryopreserved, be sure the collection facility is aware of this and proceed with caution.
If you have any questions about this change in process, contact your liaison (DonorServicesLiaisons@nmdp.org) for assistance.
Essential Collections at Apheresis and Collection Centers (updated 3/24/20)
We understand that health systems are under tremendous strain. Many health care organizations are suspending all non-essential care and procedures due to the COVID-19 pandemic. While we anticipate a significant decline in all types of BMT procedures over the next several weeks, we are confident that decisions to move forward with BMT are being made with the best interest of patients in mind. These are the patients whose lives are in greatest jeopardy without BMT and who have the most to benefit from it.
In order to continue to deliver on the promise to connect our donors with their patients, we have urged medical directors and primary coordinators at our partner apheresis and/or marrow collection centers to continue to partner with us in bringing this
Please contact Amy Hines, RN, BSN, Director, Collection Experience, at email@example.com or 231-668-7143 with any questions.
Travel and Logistics
Re-evaluation of Donor Travel (updated 3/19/2020)
To mitigate travel issues that could arise for donors before and after donation, the NMDP/Be The Match is re-evaluating where donors are traveling for collection. At this time, we are working to move donors’ collections to centers as close to their home as possible.
We recommend all Network donor centers also evaluate donor travel to decrease any potential travel issues. We also recommend having donors collect locally whenever feasible.
Consider working with your Case Managers to develop the best plan to meet patient and donor needs. Please reach out to your Partner Liaisons if you need assistance with alternative plans.
COVID-19 Impacts on Vendor Partners (updated 3/19/2020)
The NMDP/Be The Match has been in communication with our vendor partners to discuss the COVID-19 impact to their operations across the country:
- FedEx has reported they may encounter delays impacting shipments.
- LabCorp has reported that some Patient Service Centers (PSC) are closing for an undetermined length of time due to COVID-19 concerns. LabCorp leadership will provide updates on further closures.
- Concentra has no plans to reduce the number of NMDP/Be The Match donors they see for physical exams.
However, we do not foresee that the above changes will have significant impact on our operations.
Membership, Engagement, Enrollment and Experience Live Drives Paused (updated 3/26/2020)
The NMDP/Be The Match is extending the pause of all live drive recruitment activities through April 30, 2020. Our leadership will not deploy employees, contractors or volunteers to participate in live drive activities during this timeframe.
Recruitment through online registration will continue during this time. We encourage our Network partners to mobilize mission advocates, drive sponsors and other community supporters to take part in the #Couch2Cure campaign.
We will provide Account Managers and Network partners with tools and training on how to shift recruitment efforts to online activities.
Cancellation of Be The Match Mexico Recruitment Events (updated 3/19/2020)
All Be The Match Mexico recruitment events have been canceled through April 19. These dates align with the message to the public from Mexican government officials urging all schools, corporations and public events to extend their spring break (holy week vacations) from two weeks to one month. This cancellation includes all recruitment activity.
Donor Center Resources
Donor Services Webinar (updated 3/26/19)
The Donor Services webinar call on March 19, 2020, included information on COVID-19. The webinar recording is now available. Meghann Cody, DNP, APRN, NP-C, Senior Manager of Medical Services, NMDP/Be The Match presented information on:
- Changes to the Health History Screening Questionnaire, which now includes questions to identify donors with the highest risk of COVID-19 exposure
- The requirement for cryopreservation of all stem cell products, with few exceptions
- Screening donors at various timepoints, as well as providing education on timely reporting of symptoms or exposures.
You can access the COVID-19 information at the 14:48 minute mark. A PowerPoint of the presentation is also available.
Please contact your liaison (DonorServicesLiaisons@nmdp.org) with any questions regarding this or future webinar calls.
Frequently Asked Questions
Frequently Asked Questions for Donor Centers and Your Donors (updated 3/20/2020)
This information will be updated as changes occur. Click on the question to expand the answer.
Donor Center Frequently Asked Questions
What is COVID-19?
Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China.
The first case of COVID-19 in the United States was reported on Jan. 21, 2020. The current count of cases of COVID-19 in the United States is available on the Centers for Disease Control and Prevention’s (CDC) website.
Additional information from the CDC website that you may find useful includes:
Can the virus be transmitted from donor to recipient via blood or stem cells?
At this time, there is no evidence that this virus is transmitted via blood or stem cell products. For this reason, regulatory agencies do not currently recommend or require any action on product testing.
Even if the virus is not transmitted by stem cell products, ill patients can be harmed in other serious ways. This is especially true if a donor is unable to provide a stem cell product in the time needed for that recipient’s treatment or after the recipient has started their preparatory regimen.
How are potential donors being screened for this infection?
We are gathering additional health and travel information from donors at the confirmatory typing, held for workup and workup stages. This information is based on known risks. Transplant centers are informed of any identified risks to allow them to make a risk/benefit decision on whether to proceed with that donor.
Access a summary of the addendum to the Health History Screening Questionnaire:
Are there alternatives to donors traveling for donation?
Possibly. As you know, donation is time sensitive. Any delay can negatively impact the recipient’s wellbeing, especially if they have already started myeloablative prep or conditioning.
It may be possible to arrange for donation to occur at a local facility or somewhere within driving distance depending on site availability. In some cases, this may require the donor to undergo repeat testing and/or physical exam for clearance.
We respect our donors’ decisions not to travel if they feel uncomfortable doing so. Please encourage donors to speak up sooner rather than later if they are having second thoughts about traveling for donation so we can look at alternative options.
Your National Marrow Donor Program® (NMDP)/Be The Match® Liaison or Case Manager can assist with the escalation if your center does not have a local collection site.
Will you be screening or testing donors after donation? Should we test and/or quarantine the stem cell products?
At this time, there is no evidence that COVID-19 is transmitted via blood, bone marrow or stem cell products. For this reason, NMDP/Be The Match, in conjunction with other regulatory agencies such as the FDA and AABB, does not currently recommend or require product testing or quarantine.
In effort to identify donors who may have or be at risk for contracting the novel coronavirus, the NMDP/Be The Match is screening donors prior to donation at confirmatory typing, held for workup, and formal workup stages.
Following donation, donors will be contacted at regular intervals: 2 days post; 1 week post; 1 month post; and in between as needed. Additionally, all donors are being counseled to contact their individual workup specialists if they are diagnosed with COVID-19, learn of exposure to a person diagnosed with COVID-19, or develop any acute infectious symptoms prior to and following donation.
Pre-donation screening and pertinent post-donation findings will be reported to the transplant center. The NMDP/Be The Match does not recommend delaying transplant to await post-donation findings, product quarantine or product testing. That said, these decisions are at the discretion of the individual transplant center/team.
Do the side effects of filgrastim mimic some signs and symptoms of COVID-19?
The following are the most common/classic symptoms of COVID-19 infection and may appear 2 to 14 days after exposure:
- Shortness of breath
The most common side effects of filgrastim are headache, bone or muscle pain, nausea and fatigue. Less frequently, filgrastim may cause fever or dry cough. Filgrastim does not routinely cause acute shortness of breath. These symptoms typically appear within the first 24 hours of the first injection and continue until a day or two after donation.
How do I assess a potential donor who is quarantined due to exposure to COVID-19?
Any potential donor who is under quarantine due to exposure to known or suspected COVID-19 should be made temporarily unavailable (TU) for 30 days from the start of their exposure. This does not include donors working from home due to personal choice or company-wide policy. Exceptions to this guidance may be considered on a case-by-case basis in consultation with the NMDP/Be The Match and transplant center medical directors.
Quarantine in general means the separation of a person or group of people reasonably believed to have been exposed to a communicable disease but not yet symptomatic from others who have not been exposed so as to prevent the possible spread of the communicable disease.
Are couriers required to quarantine after traveling domestically or internationally with product for NMDP/Be The Match?
NMDP/Be The Match is following the CDC guidelines for both international and domestic travel at this time.
International Travel: The current CDC recommendations include self-quarantine for 14 days and practicing social distancing when returning from high-risk countries. Please check the CDC high risk travel page for regular updates to their list of countries in the Level 3 risk category. Travel FAQs for all international travel at this time are also recommended for review.
Domestic Travel: Currently, travel within the United States is not restricted. We recommend making yourself familiar with the CDC guidelines for travel within the United States before making decisions about courier trips.
We are obligated to follow the government’s guidance, and the current guidance is a recommendation of self-quarantine, not a mandatory order for situations where you have potentially been exposed to COVID-19. We ask that all couriers to read the CDC information, work to understand it, and make the appropriate decisions for themselves when accepting courier trips during this time.
Donor Frequently Asked Questions
I am concerned about traveling for donation. What can I do to protect myself?
We understand you may be concerned about air travel and exposing yourself to potential risks. If traveling for donation will affect your ability to return to work or other duties, let us know right away. We will look for alternative options for your donation.
Be The Match is monitoring travel recommendations from the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) and travel guidelines accordingly. At this time, the CDC has not restricted travel within the United States.
You may want to review the actions your airline is taking to reduce their passengers’ exposure to the virus. Your airline’s website should provide this information.
Be The Match is not asking any donors to travel to or from any locations that the CDC considers level 2 or 3. The CDC does not recommend canceling or postponing travel to destinations with level 1 travel notices because the risk of COVID-19 is thought to be low.
You can find additional information about risk locations on the CDC website:
When you travel, the CDC recommends taking the following precautions:
- Avoid contact with sick people.
- Clean and disinfect frequently touched objects and surfaces using a regular household cleaning spray or wipe.
- Avoid touching your eyes, nose or mouth with unwashed hands.
- Clean your hands often by washing them with soap and water for at least 20 seconds or using an alcohol-based hand sanitizer that contains 60-95% alcohol. Soap and water should be used if hands are visibly dirty. It is especially important to wash your hands after going to the bathroom; before eating; and after coughing, sneezing or blowing your nose.
The CDC website provides additional information on everyday preventive actions you can take to help prevent the spread of respiratory diseases:
Are there alternatives to traveling for donation?
If you feel uncomfortable traveling, we respect your decision. However, it is extremely important that you tell us right way so we can look for alternatives. Donation is time-sensitive, and any delay can have a negative impact on the recipient’s wellbeing.
It may be possible to arrange for donation to occur somewhere within driving distance. This may require that you have repeat testing and/or physical exam.
(Note for donor centers: Information on safe travel is provided in the question above.)
Should I wear a mask during workup, travel and/or the donation itself?
While you may choose to wear a mask, we currently follow the CDC recommendations for using a facemask. The CDC does not recommend that people who are well wear a facemask.
From what is known, the transmission of the coronavirus is generally limited to the distance you cough or sneeze. This is about six to eight feet. If a person with flu-like symptoms wears a mask, they will sneeze into the mask instead of the air around them.
For a healthy person, wearing a mask is not guaranteed to protect you against any virus, especially if the mask doesn’t fit properly. The coronavirus particles are smaller than those filtered by most masks, so they won’t necessarily block them.
The CDC recommends appropriate handwashing as the most effective way to minimize exposure. Learn more about the five steps you can take to reduce the spread of illness and stay healthier:
What is cryopreservation of stem cells and why is it being recommended for my donation?
Cryopreservation is the freezing of stem cells. After your donation, your cells will be sent to your recipient’s transplant center. The transplant center will freeze and store your cells until the recipient is ready for transplant.
Because travel and logistics recommendations are changing rapidly, Be The Match is recommending that transplant centers consider cryopreservation. This allows you to make your donation before a patient begins their time-sensitive preparation regimen. It helps transplant centers avoid any issues that could occur if you are unable to donate on the prearranged date.
What happens if I get sick during travel for donation?
Be The Match will cover the costs for your assessment, testing and/or treatment of your illness if you acquire COVID-19 or any other infection as a result of travel for donation.
Does bone marrow or stem cell donation compromise my immune system? Will I be at increased risk of contracting an infection or having trouble fighting an infection after donation?
No – we do not have any evidence to show that bone marrow or stem cell donation negatively affects a donor’s immune function or makes them more prone to illness after donation. Volunteer donors tend to be at lower risk of infection than the general population due to being young and healthy. A donor’s risk contracting COVID-19 or other infections is no greater than other adults in their age range.
As always, we strongly encourage good hygiene practices to keep you safe and free of infection.
Does filgrastim put me at a higher risk of infections?
The NMDP/Be The Match follows all donors of PBSC for adverse events, including signs and symptoms of infection. In over 35,000 donors, we have not seen an increase in infections in our donors. In transplant patients, filgrastim is actually used to increase the white blood cell count to speed engraftment and reduce risk of infection.
Frequently Asked Questions for Apheresis Centers and Collection Centers (updated 3/27/2020)
This information will be updated as changes occur. Click on the question to expand the answer.
When Processing Product for a Transplant Center
Does the NMDP/Be The Match have any requirements for how the product is processed/cryopreserved?
No, we expect your center to follow your own internal processes and procedures.
What additional testing should I do on the product?
We expect your center to conduct all testing in accordance with the NMDP/Be the Match product analysis document and any additional testing required by your center’s internal processes and procedures.
What results do I document on the NMDP/Be The Match product analysis?
The results documented on the F770 (HPC-A) or F772 (HPC-M) should be those of the standard post-processing product.
How much will our center be reimbursed for cryopreservation and storage of the product and how do I bill for this?
Your AC/CC Liaison will connect with your center to provide this information.
How do I label the product?
We expect your center to follow ISBT 128 labeling processes for all cryopreserved products.
Your PBSC protocol states that cryopreservation should only be done at the transplant center. Is there a variance for this and how can I get a copy?
A variance will be provided to you.
Cryopreservation Storage/Shipment When Storing/Shipping Product for a Transplant Center
How long am I expected to store the product on behalf of the transplant center?
The Case Manager will discuss a proposed shipment date with the transplant center at the time of the cryopreservation request and inform your center. The typical turn-around time thus far is 2-5 days.
Who is making the arrangements for the product to go to the transplant center?
The NMDP/Be The Match will coordinate the pickup and shipment of the cryopreserved product.
Are we required to provide our own shipping container?
We may ask if your center has availability to provide your own shipping container. If it is not feasible, the NMDP/Be The Match will provide one to your Center.
What source documents do we need to provide to the transplant center to explain the processing and pre/post product testing?
We expect that your center will provide the transplant center with the document you normally provide the end user of a cryopreserved product ex (e.g., process, additives, sterility, etc.). REMINDER: You must redact the donor’s PPI from all source documents and include the donor’s GRID on each document.