Introduction to HLA


This introductory overview describes HLA and the factors that may affect HLA matching.

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Target Audience

NMDP/Be The Match Network partners, nurses, laboratory technologists, and other healthcare professionals who work in the field of marrow and cord blood transplantation. 

Learning Objectives

  1. Describe Human Leukocyte Antigens (HLA)
  2. Define self and non-self cells and their role in the immune system
  3. Identify factors that may affect HLA matching
  4. Describe how the NMDP supports our mission to save lives by having a better understanding of HLA


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Immunogenetic Operations & Research spearheaded the creation of the HLA education series with the help of Case Management and NMDP Education and Training. The Immunogenetic Operations & Research department is responsible for understanding the scientific aspects of hematopoietic cell transplantation data, ensuring the timely acquisition and validation of these data for searching patients, and translating the evolving science into actionable policies, practices, and services.