HLA and Search Strategy
Learn about the role of HLA in HCT, the latest HLA matching guidelines, and donor and cord blood search strategies.
HLA Basics and Matching Guidelines
- HLA Education Series
This series offers basic to advanced training on the role of HLA in cellular transplantation.
- HLA Typing Resources
Resources for general and specific information on human leukocyte antigen (HLA) typing.
- HLA Matching Guidelines
Understand NMDP and CIBMTR matching guidelines and criteria for selection of marrow, PBSC, and CBUs.
- Applying HLA Matching Guidelines
Review case studies to apply the latest HLA matching guidelines for HCT patient cell source selection.
- It's Not Me: The Role of HLA in Tissue Compatibility
Learn about the basic concepts in the recognition of foreign HLA by the immune system and the application of these concepts to mismatched donor selection based on non-inherited maternal antigens or the presence of donor-specific antibodies to HLA will be discussed.
- Cord Blood Unit Selection
Understand factors used for CBU selection, including HLA match, cell dose, and single/double cord HCT.
- Donor Matching
Understand the advances in HLA typing, including clinical and technological innovations.
- Donor Search Strategies
Learn about the latest in donor search strategies to speed the search process.
- Donor Selection Beyond HLA
Review published evidence on the role of non-HLA factors as determinates of survival and highlights of new data regarding factors that may affect donor availability.
- Unrelated Donor and Cord Blood Selection Guidelines
Review the updated selection guidelines from the NMDP and CIBMTR on appropriate typing strategies and matching criteria for unrelated adult donor and CBU selection, presented at the 2012 Council Meeting.
- Genetic Ancestry for a Better Match: What We've Done so Far
Discover two novel studies currently in progress within the Bioinformatics Research Department including a study on the effects of genetic ancestry donor/recipient matching on transplant outcomes.
- New Research on the Selection of Unrelated Donors for Transplantation
Review the findings of several recent CIBMTR studies evaluating the role of low expression loci (HLA-DQ, DP and DRB3/4/5), unidirectional mismatches and donor characteristics (blood type, age and CMV) on unrelated donor transplant outcomes.